CONICET fellowships call 2016
positions are offered to apply for doctoral or postdoctoral fellowship from CONICET in the call of this year
General requirements for applicants
– doctoral fellowship: be a graduate or student received very next race of Chemical Sciences, Biology, Biotechnology, or related. preferably, but not exclusive, with overall higher than 7,50. Send CV with qualifications obtained during the course, including aplazos.
– postdoctoral fellowship: possess a doctorate degree in Chemistry, Biological or related field or certify completion before 1 April 2017. Send full CV detailing the theme of Doctoral Thesis.
For customized and more information on research topics, contact Principal Investigators
Research topics
Open call for applications to CONICET doctoral or post-doctoral fellowship, 2016
General requirements for applicants
- Doctoral Fellowship: Degree in Chemistry, Biology, Biotechnology or related fields such. Preferably , but not exclusive, grade higher than 7.50. Send CV with qualifications.
- Postdoctoral fellowship: Ph.D. in Chemical Sciences, Biological Sciences or related field or certify completion before 1 April 2017. Send full CV detailing the subject of the doctoral thesis .
For particualr requirements and more information on research topics, contact the Principal Investigators
Research topics (Spanish only)
1-Amphiphilic drugs interaction with lipid membranes model
Synopsis: Unlike drug screening to achieve specific interaction with protein receptors, compounds that interact with biological membranes seldom do through specific interactions, but as a summation of weak interactions and entropic factors. This perspective in the search for drugs must be nourished by the study of artificial models under extreme control of their properties. A thorough knowledge of the dynamics control systems and self-organized structure of lipid allows us us to study the changes that produce relatively water soluble drugs, on lipid membranes and how different membranes are able to discriminate or favor the insertion of certain drugs.
Principal Investigator: Dr. Maria Laura Fanani
Position Type: I postdoc
Contact us: lfanani@fcq.unc.edu.ar
2-Transport and intracellular metabolism of glycolipids and acylated proteins
Synopsis: Laboratory of Cellular and Molecular Biology of the CIQUIBIC-Dept.. de Qca. Biological, I. Chemical Sciences, UNC, You are interested in incorporating advanced students or graduates of careers related to Cs. Chemical, biological, Medical or other related to compete for grants from CONICET, announcement 2016, to carry out a Doctoral Thesis.
The Laboratory has own financing, national and international, and collaborations with laboratories from Argentina and abroad in the area of Cellular and Molecular Biology, with particular interest in Intracellular metabolism and transport of glycolipids and acylated proteins. For more information on the research area, scientific production and laboratory visit: http://ciquibic.fcq.unc.edu.ar/integrantes/daniotti-jose-l/
Principal Investigator: Dr. Jose Luis Daniotti
Position Type: Doctorate
Contact us: daniotti@fcq.unc.edu.ar
3-cell membranes: Modulation properties
Synopsis: The appearance of the plasma membrane has been one of the most crucial steps in the evolution. This special organelle functions as an active interface between the cell and its environment. To fulfill its functions, it is essential that possess permeability, adjustable structure and plasticity.
Our goal is to understand how the structure is modulated, permeability and mechanical properties of cell membranes. interests us understand the effect of changes in the composition of the membrane and the surrounding medium, in protein structure and cytoskeletal. More details: http://ciquibic.fcq.unc.edu.ar/integrantes/wilke-natalia/
responsible researcher: Natalia Wilke
Position Type: Doctorate, I postdoc
Contact us: wilke@fcq.unc.edu.ar
4-Molecular Biophysics synucleinopathies
Synopsis: Amilode aggregation of the protein-synuclein is the common denominator of a heterogeneous group of neurodegenerative disorders such as Parkinson's disease and multiple system atrophy. Oligomers soluble prefibrilares and insoluble amyloid fibers play a central role in neurotoxicity and progression of pathologies. The overall objective within the framework of this research is the understanding of the structural and thermodynamic bases that govern the formation of these neurotoxic species. We employ a multidisciplinary experimental approach including molecular biology techniques, optical spectroscopy and fluorescence, Fluorescence microscopy and cell assays. More information: http://ciquibic.fcq.unc.edu.ar/integrantes/celej-soledad/
responsible researcher: M. Soledad Celej
Position Type: Doctorate, I postdoc
Contact us: mcelej@mail.fcq.unc.edu.ar
5-Monolayers systems, bilayers and multilayers applied to the study of stability, structural dynamics of biomembranes and microheterogeneity
Synopsis: structuring biomembranes are studied in the plane (morphology and composition of domains, line voltage and surface pressure, dipolar repulsion among other), the relationship between these variables and they occupy the third dimension, perpendicular to the membrane ( thickness, electron density profile, spacing between bilayers, degree of correlation, coherence length, parameter CaillC, etc). The models consist of monolayers, bilayers and multilayers in different configurations, with coupling microscopic techniques (fluorescence) and light scattering (mic. Brewster angle) Synchrotron x-rays of (GIXOS, GUIDE, XRD, Aiming, SAXS) and neutrons (WITHOUT). http://www.conicet.gov.ar/new_scp/detalle.php?keywords=Rafael Oliveira&id=24575&articles = yes
Principal Investigator: Rafael Gustavo Oliveira
Position Type: Doctorate, I postdoc
Contact us: rafaelg_oliveira@yahoo.com.ar
6-Studies involving rab 1 and integrin in brain development
Synopsis: The project aims to study the involvement of rab21 protein in neural migration and development of two adhesion proteins: Precursor protein amiloiden (APP) and integrin. This study how rab21 protein regulates trafficking of proteins in the membranes of said developing neurons and their involvement in neurite outgrowth and neuronal migration. cell biology techniques were used cultures of hippocampal neurons and in brain studies in vivo using electroporation and uterus in high resolution microscopy. These studies will increase understanding of the roles of APP in neuronal development in relation to Alzheimer's disease and intellectual deficit in people with Down syndrome.
Principal Investigator: Dr. Santiago Quiroga
Position Type: Doctorate
Contact us: squiroga@fcq.unc.edu.ar
7-Mitochondrial functions that contribute to plant immunity
Synopsis: We study molecular aspects, Biochemical and cellular immunity in the plant Arabidopsis-Pseudomonas pathosystem. A key aspect of this bacteria resistance against oxidative stress is produced by cells infected by stimulating defenses in the rest of the body. Intends to investigate whether the mitochondria contributes to such stress, by the action of proline dehydrogenase (Manufacturers to ensure). Working with mutant and over-expressors plants ProDH genetic and metabolic alterations identified derived from activation. If ProDH generates mitochondrial oxidative stress will be evaluated and if it interacts with other enzymes of this route. The results help determine the mechanism by which regulates plant immunity ProDH.
responsible researcher: Dr. Maria Elena Alvarez
Position Type: Doctorate, I postdoc
Contact us: malena@mail.fcq.unc.edu.ar
8-Identification of inhibitors of protein palmitoyltransferases, interest in human health, Chemical-Genetic through strategies
Synopsis: The S-acylation or protein palmitoylation, It affects mediated by Ras signaling and its transforming activity, It is very abundant in synaptic proteins, where you contribute to plasticity and mutations in palmitoyltransferases PATs have been associated with cancer, Mental retardation, schizophrenia and other disorders of the central nervous system. Palmitoylation of some proteins of protozoan parasites is essential for the invasion of host cells. For this, There is great interest in achieving specific inhibitors of S-acylation.
The project is focused on generating assays in yeast to isolate specific inhibitors of PATs of interest expressed in Saccharomyces cerevisiae heterologously, either from mammals or parasites
Principal Investigator: Dr. Javier Valdez Taubas
Position Type: I postdoc
Contact us: jvaldezt@dqb.fcq.unc.edu.ar