Posdoctoral fellow CONICET
Director: Beatriz Caputto
Epigenetic control of transcription
The three dimensional organization of chromosomes determines the way the DNA sequence is interpreted in multiple cellular processes such replication, replication and transcription. Epigenetic regulation modifies chromatin properties that elicit structural changes and ultimately, transcriptional changes. The epigenetic regulation involves DNA methylation and histone post-traduccional modifications. The project aims to study mechanism of transcriptional regulation in cellular differentiation by developing fluorescence microscopy methods combined with DNA and RNA labeling techniques.